106243-23-6, 4-(1H-imdazol-4-yl)piperidine is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,106243-23-6
EXAMPLE 1 4-(1-CYCLOHEXYLAMINOTHIOCARBONYL-4-PIPERIDYL)-1H-IMIDAZOLE 1.4 g (0.0092 mole) of 4-(4-piperidyl)-1H-imidazole and 1.42 g (0.010 mole) of cyclohexyl isothiocyanate are brought to reflux for 2 hours in 100 cm3 of anhydrous toluene. Precipitate formed on cooling is drained, washed with anhydrous ethyl ether, dried and recrystallized in toluene. White powder, M.p. (d.) 170 C., w=2 g. 74% yield. IR spectrum (KBr): 3240 (NH). Principal bands: 2920, 2840, 1520, 1440, 1350, 1330, 1250, 1175, 1090, 970, 830, 755 and 695 cm-1. NMR spectrum: DMSO-d6 deltaH, imidazole: 7.45 and 6.66. coupling constant JH2-H5 =0.90 Hz. deltaNH: 7.13 and 7.05 ppm. deltaH piperidine and cyclohexyl: 4.61, 4.16, 2.98, 1.76 and 1.20 ppm.
As the paragraph descriping shows that 106243-23-6 is playing an increasingly important role.
Reference£º
Patent; Institut National de la Sante et de la Recherche Medicale (Inserm); Universite de Caen; Societe Civile Bioprojet; US4707487; (1987); A;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem