Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， name: 2-Amino-1-(piperidin-1-yl)ethanone hydrochloride, Which mentioned a new discovery about 5437-48-9
The one-step conversion of aliphatic carboxylic acids to the corresponding nitriles has been accomplished via the merger of visible light mediated photoredox and cyanobenziodoxolones (CBX) reagents. The reaction proceeded in high yields with natural and non-natural alpha-amino and alpha-oxy acids, affording a broad scope of nitriles with excellent tolerance of the substituents in the alpha position. The direct cyanation of dipeptides and drug precursors was also achieved. The mechanism of the decarboxylative cyanation was investigated both computationally and experimentally and compared with the previously developed alkynylation reaction. Alkynylation was found to favor direct radical addition, whereas further oxidation by CBX to a carbocation and cyanide addition appeared more favorable for cyanation. A concerted mechanism is proposed for the reaction of radicals with EBX reagents, in contrast to the usually assumed addition elimination process.
Because enzymes can increase reaction rates by enormous factors and tend to be very specific, name: 2-Amino-1-(piperidin-1-yl)ethanone hydrochloride, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 5437-48-9
Reference：
Piperidine – Wikipedia,
Piperidine | C5H10844N – PubChem