Related Products of 25137-00-2, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 25137-00-2, Name is (R)-Piperidine-3-carboxylic acid, molecular formula is C6H11NO2. In a Article,once mentioned of 25137-00-2
We examine the relationship between covalent structure and conformational propensity among a series of beta-amino acid tetramers. These experiments focus on the hairpin folding motif. Among conventional peptides, the minimum increment of beta-sheet secondary structure is a ‘beta-hairpin,’ in which two strands are connected via a short loop. The present studies are aimed at optimizing hairpin stability among beta-peptides. Previous work from our laboratory has identified optimal substitution patterns for residues that form strands in an antiparallel beta-peptide sheet (Krauthauser et al. J. Am. Chem. Soc. 1997, 119, 11719), and we have shown that a dinipecotic acid segment can promote sheet-type interactions between attached strand residues (Chung et al. J. Am. Chem. Soc. 1998, 120, 10555). Here we compare all four possible configurations of the dinipecotic acid segment, (R,S), (S,R), (R,R) and (S,S), for the ability to induce sheet formation with a constant set of enantiomerically pure strand residues. We show that both heterochiral dinipecotic acid segments promote hairpin formation, although one is distinctly superior. Neither of the homochiral dinipecotic acid supports hairpin folding. When the strand residues are beta-alanine (achiral), the heterochiral dinipecotic acid segment is again superior to the homochiral segment, but we find a difference between hairpin conformations in solution and in the solid state.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Related Products of 25137-00-2, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 25137-00-2, in my other articles.
Reference:
Piperidine – Wikipedia,
Piperidine | C5H5003N – PubChem