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A simple and facile protocol for palladium-catalyzed picolinamide-directed C8-H amination of 1-naphthylamine derivatives with simple secondary aliphatic amines was developed, thereby providing a new route to 1,8-naphthalenediamine derivatives. It is noteworthy that the picolinamide moiety as a bidentate directing group may play a key role in this regioselective transformation.
One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Related Products of 73874-95-0, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 73874-95-0
Reference：
Piperidine – Wikipedia,
Piperidine | C5H14386N – PubChem