A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, SDS of cas: 127294-73-9, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 127294-73-9, Name is (R)-Piperidin-3-amine, molecular formula is C5H12N2. In a Article, authors is Cabello-Sanchez, Noemi,once mentioned of 127294-73-9
The chemoselectivity of the palladium-mediated reaction of bromobenzene with various heterocyclic diamines was studied. Whatever the ligand used, 3-aminopyrrolidine underwent arylation of the secondary amine function (> 82%), whereas the more flexible 3-aminoazepinine was arylated on its primary function (>70%). The ratio “arylation of primary amine versus arylation of secondary amine” of 3-aminopiperidine with bromobenzene varied from 90:10 (BINAP, electron-enriched and hindered biphenyls L2 or L3) to 32:68 with the Josiphos-type ligand L10. The same trend was observed when 4-aminopiperidine was used (82:18 with L2 and 17:83 with L10). This selectivity can be tuned by the choice of aryl halide partners having different steric and electronic properties. A cooperative effect of both nitrogens of diamines during the reaction was deduced from competitive experiments. Finally, 13C and 31P NMR experiments, carried out with 3-aminopyrrolidine at room temperature, support a fast coordination of the primary amine to the metal. Indeed, a palladium complex resulting from the unusual displacement of one phosphane group of the intermediate ArPdX(BINAP) by the primary amino group was characterized.
Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about is helpful to your research. SDS of cas: 127294-73-9
Reference:
Piperidine – Wikipedia,
Piperidine | C5H540N – PubChem