Brief introduction of tert-Butyl 4-methylenepiperidine-1-carboxylate

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Reference of 159635-49-1, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 159635-49-1

Reference of 159635-49-1, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.159635-49-1, Name is tert-Butyl 4-methylenepiperidine-1-carboxylate, molecular formula is C11H19NO2. In a Letter，once mentioned of 159635-49-1

A general pharmachophore model for various types of Ser/Thr kinases was developed. Search for the molecules fitting to this pharmacophore among ASINEX proprietary library revealed a number of compounds, which were tested and appeared to possess some activity against several Ser/Thr kinases such as Aurora A, Aurora B and Haspin. The possibility of performing the fine-tuning of the general Ser/Thr pharmacophore to desired types of kinase to get active and selective inhibitors was exemplified by Aurora A kinase. As a result, several hits in 3?5 nm range of activity against Aurora A kinase with rather good selectivity and ADME properties were obtained.

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Reference of 159635-49-1, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 159635-49-1

Reference：
Piperidine – Wikipedia,
Piperidine | C5H13152N – PubChem