Analyzing the synthesis route of 769944-78-7

The synthetic route of 769944-78-7 has been constantly updated, and we look forward to future research findings.

769944-78-7, 1-N-Boc-4-(4-Bromophenyl)piperidine is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

769944-78-7, A mixture containing 4-(4-bromo-phenyl)-piperidine-1 -carboxylic acid tert-butyl ester (100 mg, 0.29 mmol), 2-tribupsilontylstannanyl-pyrimidi?e (130 mg, 0.36 mmol), cesium fluoride (85 mg, 0.56 mmol) and palladium di-tert-butylphosphine was degassed three times with Ar. Dioxane was added and the formed reaction mixture was stirred at HO 0C overnight under Ar. Then the reaction mixture was filter through celite and the .solvent was removed under vacuum and crude product was used directly in the next step.

The synthetic route of 769944-78-7 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; SCHERING CORPORATION; WO2007/70398; (2007); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem