Awesome Chemistry Experiments For 41838-46-4

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Related Products of 41838-46-4, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.41838-46-4, Name is 4-Amino-1-methylpiperidine, molecular formula is C6H14N2. In a article,once mentioned of 41838-46-4

Infections caused by hepatitis C virus (HCV) are a significant world health problem for which novel therapies are in urgent demand. The polymerase of HCV is responsible for the replication of viral genome and has been a prime target for drug discovery efforts. Here, we report on the further development of tetracyclic indole inhibitors, binding to an allosteric site on the thumb domain. Structure-activity relationship (SAR) studies around an indolo-benzoxazocine scaffold led to the identification of compound 33 (MK-3281), an inhibitor with good potency in the HCV subgenomic replication assay and attractive molecular properties suitable for a clinical candidate. The compound caused a consistent decrease in viremia in vivo using the chimeric mouse model of HCV infection.

We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 41838-46-4, and how the biochemistry of the body works.Related Products of 41838-46-4

Reference:
Piperidine – Wikipedia,
Piperidine | C5H1980N – PubChem