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The invention belongs to the technical field of preparing raw materials, in particular to a improved process for the preparation of advantage Geleg sandbank. The present invention provides a method for preparing advantage Geleg sandbank, in advantage Geleg sandbank two-step condensation reaction of the acid to be used in water-free controlled particle size of sodium carbonate is a micrometer range, the reaction does not need to use the iodide catalyst, the reducing reaction temperature, reaction time is shortened, and the two-step reaction is changed into “one-pot synthesis” preparation have high purity, high yield key intermediate of compound E. The preparation method of this invention is suitable for industrial mass production of advantage Geleg sandbank, and, ultimately, to obtain high-purity, advantage Geleg sandbank of high extraction rate. (by machine translation)

Because enzymes can increase reaction rates by enormous factors and tend to be very specific, Quality Control of: (R)-tert-Butyl piperidin-3-ylcarbamate, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 309956-78-3

Reference：
Piperidine – Wikipedia,
Piperidine | C5H13422N – PubChem