Application of 949-69-9, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 949-69-9, Name is 1-Benzylpiperidin-4-one oxime, molecular formula is C12H16N2O. In a Article，once mentioned of 949-69-9
Mutations in leucine-rich repeat kinase-2 (LRRK2) are the most common genetic cause of Parkinson’s disease (PD). The most frequent kinase-enhancing mutation is the G2019S residing in the kinase activation domain. This opens up a promising therapeutic avenue for drug discovery targeting the kinase activity of LRRK2 in PD. Several LRRK2 inhibitors have been reported to date. Here, we report a selective, brain penetrant LRRK2 inhibitor and demonstrate by a competition pulldown assay in vivo target engagement in mice.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Application of 949-69-9, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 949-69-9, in my other articles.
Reference：
Piperidine – Wikipedia,
Piperidine | C5H15161N – PubChem