Reference of 39546-32-2, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 39546-32-2, Name is Piperidine-4-carboxamide, molecular formula is C6H12N2O. In a Article，once mentioned of 39546-32-2
The decarboxylative coupling of a carboxylic acid with an amine nucleophile provides an alternative to the substitution of traditional organohalide coupling partners. Benzoic and alkynyl acids may be directly aminated by oxidative catalysis. In contrast, methods for intermolecular alkyl carboxylic acid to amine conversion, including amidate rearrangements and photoredox-promoted approaches, require stoichiometric activation of the acid unit to generate isocyanate or radical intermediates. Reported here is a process for the direct chemoselective decarboxylative amination of electron-poor arylacetates by oxidative Cu catalysis. The reaction proceeds at (or near) room temperature, uses native carboxylic acid starting materials, and is compatible with protic, electrophilic, and other potentially complicating functionality. Mechanistic studies support a pathway in which ionic decarboxylation of the acid generates a benzylic nucleophile which is aminated in a Chan?Evans?Lam-type process.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Reference of 39546-32-2, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 39546-32-2, in my other articles.
Reference：
Piperidine – Wikipedia,
Piperidine | C5H3486N – PubChem