88763-76-2, (R)-3-Aminopiperidin-2-one is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,88763-76-2
(R) -3-Aminopiperidine -2-one (1.00g, 8.76 mmol) in CH2Cl2 (15mL) triethylamine at room temperature to a solution (1.28mL, 9.2 mmol) and di-tert- butyl carbonate(2.01g, 9.2 mmol) It was added. The reaction mixture was stirred for 12 hours at the same temperature and concentrated under vacuum. The residual crude was diluted with ether (50 mL), and filtered through a pad of celite. The filtrate was evaporated to dryness, SiO2 chromatography (50g, EtOAc 100%) was purified by, 1.65g (88%) of 2-oxo-piperidin-3-yl carbamic acid (R) -tert- butyl colorless It was obtained as a foam.
The synthetic route of 88763-76-2 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; F.HOFFMANN-LA ROCHE AG; HENDRICKS, ROBERT THAN; HERMANN, JOHANNES CORNELIUS; KONDRU, RAMA K; LOU, YAN; LYNCH, STEPHEN M; OWENS, TIMOTHY D; SOTH, MICHAEL; (50 pag.)JP5667692; (2015); B2;,
Piperidine – Wikipedia
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