Electric Literature of 4395-98-6, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C–H bond functionalisation has revolutionised modern synthetic chemistry. 4395-98-6, Name is 4-Cyanopiperidine, SMILES is N#CC1CCNCC1, belongs to piperidines compound. In a article, author is Vazquez-Amaya, Laura Y., introduce new discover of the category.
Transition-Metal-Free Total Synthesis and Revision of the Absolute Configuration of Pipermethystine
Starting from 3-hydroxy piperidines, a novel transition-metal-free strategy to 5-hydroxy-5,6-dihydro-2(1H)pyridones is reported. This unprecedented approach, which provides a practical, economical, and ecofriendly alternative to either the classical ring-closing metathesis of N-homoallyl-unsaturated amides or the dehydrogenation of amides, occurs by means of a triple C-H functionalization of three unreactive piperidine sp(3) carbons. The completion of the total synthesis revealed that the natural levoisomer possesses the R absolute configuration, not S.
Electric Literature of 4395-98-6, Consequently, the presence of a catalyst will permit a system to reach equilibrium more quickly, but it has no effect on the position of the equilibrium as reflected in the value of its equilibrium constant.I hope my blog about 4395-98-6 is helpful to your research.
Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem