91419-49-7, 1-Boc-3-Carbamoylpiperidine is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
91419-49-7, tert-Butyl 3-carbamothioyIpiperidine-l-carboxylate (92):Amide 91 (2.0 g, 8.76 mmol) and Lawesson’s reagent (1.79 g, 4.42 mmol) were stirred in toluene (45 niL) and the mixture heated to 62 C for 4 hours. The mixture was treated with 5 g of silica gel and 15 mL of methanol, and evaporated to dryness. The solid residue was chromatographed over 30 g of silica gel, eluting with CH2Cl2IMeOH (96:4). The product was chromatographed again, eluting with CH2CbMeOH (97:3) and dried to 1.33 g of 92 as a white foam. MS (ESI) m/z 283 [M+K]+. 1H NMR (CDCl3) delta 1.30-1.50 (m, 10 H), 1.55-1.65 (bs, IH), 1.9-2.0 (m, IH), 2.0-2.2 (m, IH), 2.60-2.75 (bs, IH), 3.0-3.2 (bs, IH), 3.3-3.45 (bs, IH), 3.6-3.95 (m, 2H), 7.43 (bs, 2H).
As the paragraph descriping shows that 91419-49-7 is playing an increasingly important role.
Reference£º
Patent; MITHRIDION, INC.; TWOSE, Trevor, M.; ABRAHAM, Brent, D.; COPP, Richard, R.; FARNHAM, James, G.; HANSON, Seth, A.; HENDRICKSON, Michael, L.; OCKULY, Jeffrey, C.; VERDONE, Melinda, L.; WO2010/102218; (2010); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem