In an article, author is Weglarz, Izabela, once mentioned the application of 120013-39-0, COA of Formula: C17H24ClNO3, Name is 5,6-Dimethoxy-2-(4-piperidinylmethyl)-1-indanone hydrochloride, molecular formula is C17H24ClNO3, molecular weight is 325.8304, MDL number is MFCD09033179, category is piperidines. Now introduce a scientific discovery about this category.
Zinc-Catalyzed Asymmetric Hydrosilylation of Cyclic Imines: Synthesis of Chiral 2-Aryl-Substituted Pyrrolidines as Pharmaceutical Building Blocks
The first successful enantioselective hydrosilylation of cyclic imines promoted by a chiral zinc complex is reported. In situ generated zinc-ProPhenol complex with silane afforded pharmaceutically relevant enantioenriched 2-aryl-substituted pyrrolidines in high yields and with excellent enantioselectivities (up to 99% ee). The synthetic utility of presented methodology is demonstrated in an efficient synthesis of the corresponding chiral cyclic amines, being pharmaceutical drug precursors to the Aticaprant and Larotrectinib.
If you are interested in 120013-39-0, you can contact me at any time and look forward to more communication. COA of Formula: C17H24ClNO3.
Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem