117896-69-2, 1-Phenylpiperidin-4-ol is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Example 40 Methyl AL(fe/^-butoxyearbonyl)-Methyl N-(tert-butoxycarbonyl)-L-tyrosinate (1.05 g), triphenylphosphine (1.40 g) and 4-hydroxy-l-phenylpiperidine (0.95 g) were dissolved in DCM and cooled to O0C. DTAD (1.25 g) was added slowly maintaining T< 5 0C. The reaction mixture was stirred overnight at room temperature then concentrated in vacuo and the residue purified by chromatography using iso-hexane - 10% ethyl acetate to 50% ethyl acetate as eluent to give the title compound as a yellow solid (1.91 g, 79%).1H NMR Spectrum (DMSO-d6) 1.33 (9H, s), 1.70 (2H, m), 2.04 (IH, m), 2.84 (2H, m), 3.04 (2H, t), 3.50 (2H5 m), 3.61 (3H, s), 4.12 (IH, m), 4.51 (IH, t), 6.76 (IH, t), 6.93 (4H, dd), 7.18 (5H, m).Mass Spectrum [M+H]+ = 455 117896-69-2, As the paragraph descriping shows that 117896-69-2 is playing an increasingly important role.
Reference£º
Patent; ASTRAZENECA AB; ASTRAZENECA UK LIMITED; WO2007/91046; (2007); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem