One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time. 4395-98-6, Name is 4-Cyanopiperidine, formurla is C6H10N2. In a document, author is Roy, Tarun Kumar, introducing its new discovery. Quality Control of 4-Cyanopiperidine.
Cinchonamine Squaramide Catalyzed Asymmetric aza-Michael Reaction: Dihydroisoquinolines and Tetrahydropyridines
The first example of a chiral cinchona-squaramide catalyzed enantioselective intramolecular aza-Michael addition for the synthesis of dihydroisoquinolines and tetrahydropyridines has been developed. In general, good yields and excellent enantioselctivities were observed. Broad classes of Michael acceptors, such as enones, esters, thioesters, and Weinreb amides, were successful substrates. The possibility of recycling the catalysts has also been demonstrated. An oxidation of combined enamine and keto functionalities on chiral dihydroisoquinolines leads to a single diastereomer of an architecturally unprecedented tetracyclic core without loss in enantioselectivity.
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Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem