Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 2403-88-5, Name is 2,2,6,6-Tetramethyl-4-piperidinol, molecular formula is C9H19NO, belongs to piperidines compound, is a common compound. In a patnet, author is Raj, N. Ugin Inba, once mentioned the new application about 2403-88-5, SDS of cas: 2403-88-5.
Synthesis, single crystal XRD and CT DNA/BSA binding studies of new paracetamol derivatives
N-(4-hydroxy-3-(morpholino(phenyl)methyl)phenyl) acetamide and N-(4-hydroxy-3-(piperidin-1-yl(phenyl)methyl)phenyl) acetamide derivatives have been synthesized via three component reaction of paracetamol, morpholine/piperidine and benzaldehyde. The reaction afforded these novel paracetamol derivatives in moderate to good yield. The solid state structures of some compounds were examined by X-rays from single crystals.The DNA-binding interactions of the compounds with calf thymus DNA have been studied by UV, visible, emission studies. The results were observed hypochromism with red shift suggesting that compounds interact with CT DNA via intercalation. The protein-binding interactions of the compounds with BSA were examined by fluorescence, synchronous fluorescence and UV, visible spectroscopic methods. All the compounds have the ability to bind strongly with BSA and a static quenching mechanism was observed. (C) 2020 Elsevier B.V. All rights reserved.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 2403-88-5. The above is the message from the blog manager. SDS of cas: 2403-88-5.
Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem