Reactions catalyzed within inorganic and organic materials and at electrochemical interfaces commonly occur at high coverage and in condensed media, causing turnover rates to depend strongly on interfacial structure and composition, 120013-39-0, Name is 5,6-Dimethoxy-2-(4-piperidinylmethyl)-1-indanone hydrochloride, SMILES is Cl.COC2=C(C=C1C(C(CC1=C2)CC3CCNCC3)=O)OC, in an article , author is Wu, Yong-Jin, once mentioned of 120013-39-0, Recommanded Product: 5,6-Dimethoxy-2-(4-piperidinylmethyl)-1-indanone hydrochloride.
Discovery of morpholine-based aryl sulfonamides as Na(v)1.7 inhibitors
Replacement of the piperidine ring in the lead benzenesulfonamide Na(v)1.7 inhibitor 1 with a weakly basic morpholine core resulted in a significant reduction in Na(v)1.7 inhibitory activity, but the activity was restored by shortening the linkage from methyleneoxy to oxygen. These efforts led to a series of morpholine-based aryl sulfonamides as isoform-selective Na(v)1.7 inhibitors. This report describes the synthesis and SAR of these analogs. (C) 2018 Elsevier Ltd. All rights reserved.
But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 120013-39-0, you can contact me at any time and look forward to more communication. Recommanded Product: 5,6-Dimethoxy-2-(4-piperidinylmethyl)-1-indanone hydrochloride.
Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem