Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 19916-73-5, Name is 6-(Benzyloxy)-7H-purin-2-amine, molecular formula is C12H11N5O, belongs to piperidines compound, is a common compound. In a patnet, author is Janikova, Katerina, once mentioned the new application about 19916-73-5, COA of Formula: C12H11N5O.
Chan-Lam cross-coupling reaction based on the Cu2S/TMEDA system
A catalyst based on the readily available Cu2S/TMEDA system using a stable copper(I) source was developed for the Chan-Lam cross-coupling reaction. The capability of the catalyst was demonstrated with 1H-benzo[d]imidazol-2(3H)-one, 1H-benzo[dlimidazole, and 1H-imidazole together with electron deficient, electron-rich, and sterically demanding boronic acids at room temperature in the presence of atmospheric oxygen to give the cross-coupling products in moderate to excellent yields. In addition, the coupling reaction of 1H-benzo[dlimidazole with several pinacol or neopentylglycol boronates indicated further potential of the catalyst. The reaction conditions tolerate the hydroxyl and bromo functional groups. The catalytic system also enables to synthesize the mono-N-substituted anilines from primary aliphatic amines. However, the two model compounds for the secondary and aromatic amines, piperidine and aniline, do not react. Two sterically demanding products with the restricted C-N bond rotation, synthesized by the N-arylation of 1H-benzo[d]imidazol-2(3H)-one with o-tolylboronic acid, enabled to confirm the atropisomers prepared by the Chan-Lam cross-coupling reaction. Furthermore, an example of one-pot Chan-Lam and Suzuki-Miyaura reaction has been reported. (C) 2017 Elsevier Ltd. All rights reserved.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 19916-73-5. The above is the message from the blog manager. COA of Formula: C12H11N5O.
Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem