Chemistry, like all the natural sciences, begins with the direct observation of nature¡ª in this case, of matter.10310-21-1, Name is 2-Amino-6-chloropurine, SMILES is NC1=NC(Cl)=C2NC=NC2=N1, belongs to piperidines compound. In a document, author is Hosseini, Fahimeh Sadat, introduce the new discover, Quality Control of 2-Amino-6-chloropurine.
A simple method for the rapid synthesis of 2-amino-7,7-dimethyl-5-oxo-1,4-diaryl-hexahydroquinoline-3-carboxamide derivatives
Simple synthesis of oxoquinoline carboxamide derivatives via one-pot, multi-component reaction of enaminones derived from the addition of dimedone to various anilines with aromatic aldehydes and cyanoacetamide is described. Optimal reaction conditions for the synthesis of products were obtained, when EtOH/H2O (1:1) was used as the solvent at 80 degrees C, in the presence of piperidine as the catalyst. The reactions are completed within 5-25 min, in good to high yields (74-85%). This protocol involves Michael reaction, imine-enamine tautomerization, and cyclization sequences. The structures of products were deduced from their IR, mass, H-1 NMR, and C-13 NMR spectra. This method includes some important aspects including simple operation under mild conditions, easy accessibility of reactants, workup procedure, high atom economy, and the use of ethanol/water as a green media. [GRAPHICS] .
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 10310-21-1 is helpful to your research. Quality Control of 2-Amino-6-chloropurine.
Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem