A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 188111-79-7, Name is (R)-1-Boc-3-Aminopiperidine, molecular formula is C10H20N2O2. In an article, author is Griggs, Samuel D.,once mentioned of 188111-79-7, Application In Synthesis of (R)-1-Boc-3-Aminopiperidine.
Strategies for the synthesis of spiropiperidines – a review of the last 10 years
Spiropiperidines have gained in popularity in drug discovery programmes as medicinal chemists explore new areas of three-dimensional chemical space. This review focuses on the methodology used for the construction of 2-, 3- and 4-spiropiperidines, covering the literature from the last 10 years. It classifies the synthesis of each of the types of spiropiperidine by synthetic strategy: the formation of the spiro-ring on a preformed piperidine ring, and the formation of the piperidine ring on a preformed carbo-or heterocyclic ring. While 3- and 4-spiropiperidines are predominantly synthesised for drug discovery projects, 2-spiropiperidines are synthesised en route to natural products. The lack of 2-spiropiperidines in drug discovery is presumably due to limited general procedures for their synthesis.
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Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem