179474-79-4, Name is 1-(3-Methoxypropyl)piperidin-4-amine, molecular formula is C9H20N2O, belongs to piperidines compound, is a common compound. In a patnet, author is Gu, He, once mentioned the new application about 179474-79-4, Recommanded Product: 1-(3-Methoxypropyl)piperidin-4-amine.
Total Synthesis of (-)-Lepadin F based on a Stereoselective Diels-Alder Reaction Controlled by a Ketolactone-type Dienophile
An efficient approach to the type III lepadin alkaloids (lepadins F and G) has been developed through a key Diels-Alder reaction, in which a novel ketolactone-type dienophile with chiral diol unit is employed to generate the desirable all-cis-trisubstituted cyclohexene with excellent regio- and stereoselectivity control. The subsequent selective sulfonylation of the diol unit followed by S(N)2 cyclization under hydrogenation conditions could construct the substituted piperidine ring. By using this approach, (-)-lepadin F is synthesized from ethyl l-lactate for the first time.
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Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem