Reference of 2403-88-5, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 2403-88-5, Name is 2,2,6,6-Tetramethyl-4-piperidinol, SMILES is CC1(C)CC(O)CC(C)(C)N1, belongs to piperidines compound. In a article, author is Narayanan, Arjun, introduce new discover of the category.
Superelectrophilic Activation of Phenylglyoxamides: Efficient Synthesis of Triarylacetamides and Fluorenecarboxamides by Superacid Catalysis
Direct synthesis of triarylacetamides and 9-fluorenecarboxamides has been achieved. Phenylglyoxamides upon superelectrophilic activation in trifluoromethanesulfonic acid (triflic acid, TFSA) leads to Friedel-Crafts hydroxyalkylation or one-pot tandem hydroxyalkylation-4 pi-electrocyclization of aromatics into triarylacetamides or 9-fluorenecarboxamides, respectively. Mechanistic investigation by DFT calculations suggests the intermediacy of diprotonated (or protosolvated) intermediates.
Reference of 2403-88-5, One of the oldest and most widely used commercial enzyme inhibitors is aspirin, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 2403-88-5.
Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem