50606-58-1,50606-58-1, 1-Benzylpiperidin-3-one hydrochloride is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
1-Benzyl-3-piperidine hydrochloride hydrate (1.02 g, 5.40 mmol) was suspended in methylene chloride, washed with 1 M NaOH, dried through cotton, and concentrated to give 1.02 g of free base material. The free base was dissolved in THF (40 mL) and cooled to 0 C. Phenyl magnesium bromide (3.0 M in ether, 8.10 mmol, 2.70 mL) was added dropwise over 30 min, at which point the solution was warmed to rt and stirred for 3 h. The mixture was then concentrated and the residue dissolved in methylene chloride. The resultant solution was washed with 10% saturated NH4Cl, dried through cotton and concentrated. Silica gel chromatography eluding with hexanes/ethyl acetate (3:1) gave 0.975 g of the title compound as a pale yellow oil.
50606-58-1 1-Benzylpiperidin-3-one hydrochloride 3084924, apiperidines compound, is more and more widely used in various.
Reference£º
Patent; Pfizer Inc; US2006/19975; (2006); A1;,
Piperidine – Wikipedia
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