Synthetic Route of 2008-75-5, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 2008-75-5, Name is 1-(2-Chloroethyl)piperidine hydrochloride, molecular formula is C7H15Cl2N. In a Article£¬once mentioned of 2008-75-5
1H-benzimidazole derivatives as butyrylcholinesterase inhibitors: synthesis and molecular modeling studies
A series of N-{2-[2-(1H-benzimidazole-2-yl)phenoxy]ethyl} substituted amine derivatives were synthesized and tested for their cholinesterase inhibitor activity. Acetylcholinesterase and butyrylcholinesterase inhibitor activities were evaluated in vitro by using Ellman?s method. According to the activity results, all of the compounds displayed moderate acetylcholinesterase inhibitory activity and most of the compounds displayed remarkable butyrylcholinesterase inhibitory activity. Compound 3d was the most active compound in the series and also a selective butyrylcholinesterase inhibitor. Molecular docking studies and molecular dynamic simulations were also carried out.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Synthetic Route of 2008-75-5, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 2008-75-5, in my other articles.
Reference£º
Piperidine – Wikipedia,
Piperidine | C5H11390N – PubChem