Application of 106-52-5, In heterogeneous catalysis, the catalyst is in a different phase from the reactants. At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 106-52-5, name is 1-Methylpiperidin-4-ol. In an article£¬Which mentioned a new discovery about 106-52-5
Multitarget-Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3R Antagonism for Neurodegenerative Diseases
The therapy of complex neurodegenerative diseases requires the development of multitarget-directed drugs (MTDs). Novel indole derivatives with inhibitory activity towards acetyl/butyrylcholinesterases and monoamine oxidases A/B as well as the histamine H3 receptor (H3R) were obtained by optimization of the neuroprotectant ASS234 by incorporating generally accepted H3R pharmacophore motifs. These small-molecule hits demonstrated balanced activities at the targets, mostly in the nanomolar concentration range. Additional in vitro studies showed antioxidative neuroprotective effects as well as the ability to penetrate the blood?brain barrier. With this promising in vitro profile, contilisant (at 1 mg kg?1 i.p.) also significantly improved lipopolysaccharide-induced cognitive deficits.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.106-52-5. In my other articles, you can also check out more blogs about 106-52-5
Reference£º
Piperidine – Wikipedia,
Piperidine | C5H2279N – PubChem