The important role of 1-Phenylpiperidine-4-carbaldehyde

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Synthetic Route of 111153-74-3, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 111153-74-3

Synthetic Route of 111153-74-3, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.111153-74-3, Name is 1-Phenylpiperidine-4-carbaldehyde, molecular formula is C12H15NO. In a Article£¬once mentioned of 111153-74-3

Synthesis and alpha4beta2 nicotinic affinity of unichiral 5-(2-pyrrolidinyl)oxazolidinones and 2-(2-pyrrolidinyl)benzodioxanes

The RS and SR enantiomers of 2-oxazolidinone and 1,4-benzodioxane bearing a 2-pyrrolidinyl substituent at the 5- and 2-position, respectively, were synthesized as candidate nicotinoids. One of the two benzodioxane stereoisomers reasonably fits the pharmacophore elements of (S)-nicotine and binds at alpha4beta2 nicotinic acetylcholine receptor with submicromolar affinity. Interestingly, both the synthesized pyrrolidinylbenzodioxanes exhibit analogous affinity at alpha2 adrenergic receptor resembling the behaviour of some known alpha2-AR ligands recently proved to possess neuronal nicotinic affinity.

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Synthetic Route of 111153-74-3, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 111153-74-3

Reference£º
Piperidine – Wikipedia,
Piperidine | C5H11676N – PubChem