Electric Literature of 19977-51-6, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.19977-51-6, Name is 1-(3-Bromoprop-2-ynyl)piperidine, molecular formula is C8H12BrN. In a article£¬once mentioned of 19977-51-6
Thermal transformations of tris(2-thienyl)phosphine (PTh3) at low-valent ruthenium cluster centers: Part I. Carbon-hydrogen, carbon-phosphorus and carbon-sulfur bond activation yielding Ru3(CO)8L{mu-Th2P(C4H2S)}(mu-H) (L = CO, PTh3), Ru3(CO)7(mu-PTh2)2(mu3-eta2-C4H2S), Ru4(CO)9(mu-CO)2(mu4-eta2-C4H2S)(mu4-PTh) and Ru5(CO)11(mu-PTh2)(mu4-eta4-C4H3)(mu4-S)
Reaction of Ru3(CO)12 with tris(2-thienyl)phosphine (PTh3) in CH2Cl2 at room temperature or in THF in the presence of a catalytic amount of Na[Ph2CO] furnishes the carbonyl substitution products Ru3(CO)11(PTh3) (1), Ru3(CO)10(PTh3)2 (2), and Ru3(CO)9(PTh3)3 (3). Heating 1 in toluene affords the cyclometalated cluster Ru3(CO)9{mu-Th2P(C4H2S)}(mu-H) (4) resulting from carbonyl loss and carbon-hydrogen bond activation, and both 4 and the substituted derivative Ru3(CO)8{mu-Th2P(C4H2S)}(PTh3)(mu-H) (5) resulted from the direct reaction of Ru3(CO)12 and PTh3 at 110 C in toluene. Interestingly, thermolysis of 2 in benzene at 80 C affords 5 together with phosphido-bridged Ru3(CO)7(mu-PTh2)2(mu3-eta2-C4H2S) (6) resulting from both phosphorus-carbon and carbon-hydrogen bond activation of coordinated PTh3 ligand(s). Cluster 6 is the only product of the thermolysis of 2 in toluene. Heating cyclometalated 4 with Ru3(CO)12 in toluene at 110 C yielded the tetranuclear phosphinidine cluster, Ru4(CO)9(mu-CO)2(mu4-eta2-C4H2S)(mu4-PTh) (7), resulting from carbon-phosphorus bond scission, together with the pentaruthenium sulfide cluster, Ru5(CO)11(mu-PTh2)(mu4-eta4-C4H3)(mu4-S) (8), in which sulfur is extruded from a thiophene ring. All the new compounds were characterized by elemental analysis, mass spectrometry, IR and NMR spectroscopy, and by single crystal X-ray diffraction analysis in case of clusters 4, 6, 7, and 8. Cluster 4 consists of a triangular ruthenium framework containing a mu3-Th2P(C4H2S) ligand, while 6 consists of a ruthenium triangle containing eta2-mu3-thiophyne ligand and two edge-bridging PTh2 ligands. Cluster 7 exhibits a distorted square arrangement of ruthenium atoms that are capped on one side by a mu4-phosphinidene ligand and on the other by a 4e donating mu4-eta2-C4H2S ligand. The structure of 8 represents a rare example of a pentaruthenium wing-tip bridged-butterfly skeleton capped by mu4-S and mu4-eta4-C4H3 ligands. The compounds 4, 6, 7, and 8 have been examined by density functional theory (DFT), and the lowest energy structure computed coincides with the X-ray diffraction structure. The hemilabile nature of the activated thienyl ligand in 4 and 6 has also been computationally investigated.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 19977-51-6, and how the biochemistry of the body works.Electric Literature of 19977-51-6
Reference£º
Piperidine – Wikipedia,
Piperidine | C5H15033N – PubChem