Discovery of 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole

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Thiophene compound

Thiophene compounds of the formula STR1 wherein each symbol is as defined in the specification, their pharmaceutically acceptable salts, pharmaceutical compositions containing said compound and additives for pharmaceuticals, and antipsychotics containing said compound as an active ingredient. The compound of the present invention has pharmacological actions required of antipsychotic, such as motility suppressing action, anti-apomorphine action, mothamphetamine antagonistic action, tetrabenazine-induced blepharoptosis enhancing action, and the like. The compound of the present invention is useful as an antipsychotic having less extrapyramidal side-effects or a non-benzodiazepine type antianxiety agent.

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Reference£º
Piperidine – Wikipedia,
Piperidine | C5H17750N – PubChem