Chemistry is an experimental science, category: piperidines, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 137076-22-3, Name is tert-Butyl 4-formylpiperidine-1-carboxylate
Conversion of Aldehydes to Branched or Linear Ketones via Regiodivergent Rhodium-Catalyzed Vinyl Bromide Reductive Coupling-Redox Isomerization Mediated by Formate
A regiodivergent catalytic method for direct conversion of aldehydes to branched or linear alkyl ketones is described. Rhodium complexes modified by PtBu2Me catalyze formate-mediated aldehyde-vinyl bromide reductive coupling-redox isomerization to form branched ketones. Use of the less strongly coordinating ligand, PPh3, promotes vinyl-to allylrhodium isomerization en route to linear ketones. This method bypasses the 3-step sequence often used to convert aldehydes to ketones involving the addition of pre-metalated reagents to Weinreb or morpholine amides.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. category: piperidines, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 137076-22-3, in my other articles.
Reference£º
Piperidine – Wikipedia,
Piperidine | C5H16476N – PubChem