Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 142247-38-9, molcular formula is C14H25NO4, introducing its new discovery. Quality Control of: 4-(1-(tert-Butoxycarbonyl)piperidin-4-yl)butanoic acid
Incorporation of neutral C-terminal residues in 3-amidinophenylalanine-derived matriptase inhibitors
A novel series of matriptase inhibitors based on previously identified tribasic 3-amidinophenylalanine derivatives was prepared. The C-terminal basic group was replaced by neutral residues to reduce the hydrophilicity of the inhibitors. The most potent compound 22 inhibits matriptase with a Ki value of 0.43 nM, but lacks selectivity towards factor Xa. By combination with neutral N-terminal sulfonyl residues several potent thrombin inhibitors were identified, which had reduced matriptase affinity.
One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Quality Control of: 4-(1-(tert-Butoxycarbonyl)piperidin-4-yl)butanoic acid, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 142247-38-9
Reference£º
Piperidine – Wikipedia,
Piperidine | C5H21877N – PubChem