Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 41661-47-6, molcular formula is C5H9NO, introducing its new discovery. Formula: C5H9NO
Cytotoxic Amides from Fruits of Kawakawa, Macropiper excelsum
Cytotoxic amides have been isolated from the fruits of the endemic New Zealand medicinal plant kawakawa, Macropiper excelsum (Piperaceae). The main amide was piperchabamide A and this is the first report of this rare compound outside the genus Piper. Eleven other amides were purified including two new compounds with the unusual 3,4-dihydro-1(2H)-pyridinyl group. The new compounds were fully characterized by 2D NMR spectroscopy, which showed a slow exchange between two rotamers about the amide bond, and they were chemically synthesized. In view of the antitumor activity of the related piperlongumine, all of these amides plus four synthetic analogs were tested for cytotoxicity. The most active was the piperine homolog piperdardine, with an IC50 of 14 muM against HT 29 colon cancer cells.
One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Formula: C5H9NO, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 41661-47-6
Reference£º
Piperidine – Wikipedia,
Piperidine | C5H319N – PubChem