More research is needed about 50533-97-6

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Synthetic Route of 50533-97-6, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 50533-97-6

Synthetic Route of 50533-97-6, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.50533-97-6, Name is N,N-Dimethylpiperidin-4-amine, molecular formula is C7H16N2. In a Article£¬once mentioned of 50533-97-6

Fragment-based discovery of 7-azabenzimidazoles as potent, highly selective, and orally active CDK4/6 inhibitors

Herein, we describe the discovery of potent and highly selective inhibitors of both CDK4 and CDK6 via structure-guided optimization of a fragment-based screening hit. CDK6 X-ray crystallography and pharmacokinetic data steered efforts in identifying compound 6, which showed >1000-fold selectivity for CDK4 over CDKs 1 and 2 in an enzymatic assay. Furthermore, 6 demonstrated in vivo inhibition of pRb-phosphorylation and oral efficacy in a Jeko-1 mouse xenograft model.

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Synthetic Route of 50533-97-6, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 50533-97-6

Reference£º
Piperidine – Wikipedia,
Piperidine | C5H3914N – PubChem