More research is needed about 62813-01-8

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Application of 62813-01-8, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 62813-01-8

Application of 62813-01-8, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.62813-01-8, Name is 1-Cyclopropylpiperidin-4-one, molecular formula is C8H13NO. In a Article£¬once mentioned of 62813-01-8

Synthesis and biological evaluation of allylated mono-carbonyl analogues of curcumin (MACs) as anti-cancer agents for cholangiocarcinoma

A series of new allylated mono-carbonyl curcumin analogues (MACs) were designed and synthesized. In vitro cytotoxic activities of allylated MACs 6a?h together with previously reported analogues 4a?i and 7a?e, were tested against human cholangiocarcinoma cell lines including HUCCA, QBC-939 and RBE. Of all the compounds tested, 6c exhibited potent in vitro antiproliferative activity against the three tested cancer cell lines with IC50values of 8.7, 9.3 and 8.9 muM, respectively. Cell cycle analysis showed that 6c inhibited cell proliferation due to G2/M arrest. Furthermore, mechanistic studies revealed that 6c dose-dependently increased the level of Bax and inhibited the expression of Bcl-2, to induce cancer cell apoptosis. Taken together, this work provides a novel series of anti-cancer candidates for the treatment of cholangiocarcinoma.

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Application of 62813-01-8, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 62813-01-8

Reference£º
Piperidine – Wikipedia,
Piperidine | C5H6508N – PubChem