Spectrophotometric determination of buclizine and pyrilamine in pharmaceutical formulations by Tpooo was written by Kishore, M.;Hanumantharao, Y.. And the article was included in Analytical Chemistry: An Indian Journal in 2010.Formula: C28H35Cl3N2 This article mentions the following:
A simple, sensitive, selective and accurate spectrophotometric method Tpooo for the determination of buclizine (BUCZ) and pyrilamine (PYRA) in bulk drug and pharmaceutical formulations (tablets) was described. This method is based on the extraction of drugs into organic layer of the dye Tpooo in presence of 0.1 N hydrochloric acid and the absorbances were measured at 480 nm. The results of anal. for this method have been validated statistically and by recovery studies. In the experiment, the researchers used many compounds, for example, 1-(4-(tert-Butyl)benzyl)-4-((4-chlorophenyl)(phenyl)methyl)piperazine dihydrochloride (cas: 129-74-8Formula: C28H35Cl3N2).
1-(4-(tert-Butyl)benzyl)-4-((4-chlorophenyl)(phenyl)methyl)piperazine dihydrochloride (cas: 129-74-8) belongs to piperazine derivatives. Piperazine belongs to the family of medicines called anthelmintics. Intermediate for a wide range of pharmaceuticals, polymers, dyes, corrosion inhibitors, rubber accelerators and surfactants.Formula: C28H35Cl3N2
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics