Photolysis of Tertiary Amines in the Presence of CO2: The Paths to Formic Acid, 伪-Amino Acids, and 1,2-Diamines was written by Berton, Mateo;Mello, Rossella;Acerete, Rafael;Gonzalez Nunez, Maria Elena. And the article was included in Journal of Organic Chemistry in 2018.Formula: C7H13NO2 This article mentions the following:
The photolysis of triethylamine [I] in the presence of carbon dioxide leads to the hydrogenation of CO2, the 伪-C-C coupling of I, and the CO2 insertion into the 伪-C-H 蟽-bond of amine I. This reaction is proposed to proceed through the radical ion pair [R3N鈥?路CO2鈥?] generated by the photoionization of amine I and the electron capture by CO2. The presence of lithium tetrafluoroborate in the reaction medium promotes the efficient and stereoselective 伪-C-C coupling of I by enhancing the production of 伪-dialkylamino radicals and the isomerization of N,N,N’,N’-tetraethylbutane-2,3-diamine. In the experiment, the researchers used many compounds, for example, 1-Methylpiperidine-2-carboxylic acid (cas: 7730-87-2Formula: C7H13NO2).
1-Methylpiperidine-2-carboxylic acid (cas: 7730-87-2) belongs to piperidine derivatives. The piperidine moiety constitutes an important building block for the synthesis of a variety of bioactive natural products, alkaloids and other drugs. Piperidine derivatives bearing a masked aldehyde function in the 蔚-position are easily transformed into quinolizidine compounds through intramolecular reductive amination.Formula: C7H13NO2
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem