Ionic Liquid Stabilized 2,2,6,6-Tetramethylpiperidine 1-Oxyl Catalysis for Alcohol Oxidation was written by Li, Min;Klunder, Kevin;Blumenthal, Emmy;Prater, Matthew B.;Lee, Jack;Matthiesen, John E.;Minteer, Shelley D.. And the article was included in ACS Sustainable Chemistry & Engineering in 2020.Application of 14691-89-5 This article mentions the following:
N-Oxyl reagents, particularly 2,2,6,6-tetramethylpiperidine 1-oxyl (TEMPO), have been extensively used for alc. oxidations While TEMPO-mediated oxidations are kinetically and thermodynamically favorable in high-pH electrolytes, base-induced degradation often results in significant loss of catalytic activity. Herein, we demonstrate enhanced alk. stability of a TEMPO derivative in ionic liquids (ILs). By incorporating TEMPO in an imidazole-anchored IL, no loss of current was observed at pH 10.0 after 2.0 h during the oxidation of butanol and glycerol, while TEMPO in polycaprolactone (PCL), a patternable binder material, degraded 58.5% and 67.1%, resp. The stability enhancement was further demonstrated by analyzing the conversion of glycerol in an 800渭L electrochem. cell using bulk chem. anal. techniques. Successive cycles of glycerol oxidation indicated 14-fold stability enhancement by applying IL in a TEMPO electrode composite in comparison to PCL. The strategy demonstrated here provides an opportunity to prepare catalytic systems with enhanced stability. Further, this method provides the ability to convert what are typically homogeneous catalysts to heterogeneous systems. To improve the stability of TEMPO, used to mediate oxidations for biorenewables, an ionic liquid based catalyst was developed. In the experiment, the researchers used many compounds, for example, 4-Acetamido-2,2,6,6-tetramethylpiperidine 1-oxyl (cas: 14691-89-5Application of 14691-89-5).
4-Acetamido-2,2,6,6-tetramethylpiperidine 1-oxyl (cas: 14691-89-5) belongs to piperidine derivatives. The piperidine moiety constitutes an important building block for the synthesis of a variety of bioactive natural products, alkaloids and other drugs. Piperidine derivatives are being utilized in different ways as anticancer, antiviral, antimalarial, antimicrobial, antifungal, antihypertension, analgesic, anti-inflammatory, anti-Alzheimer, antipsychotic and/or anticoagulant agents.Application of 14691-89-5
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem