Herold, Franciszek et al. published their research in European Journal of Medicinal Chemistry in 2010 | CAS: 17403-09-7

3-(Piperidin-4-yl)-1H-indole (cas: 17403-09-7) belongs to piperidine derivatives. The piperidine ring can be found not only in more than half of the currently known structures of alkaloids, but also in many natural or synthetic compounds with interesting biological activities. The piperidine and polyhydroxylated indolizidine derivatives have shown to be promising α-glucosidase inhibitors. The former are analogs of DNJ with an improved α-glucosidase inhibitory profile than that of DNJ. Boisson et al.Application In Synthesis of 3-(Piperidin-4-yl)-1H-indole

Novel 4-aryl-pyrido[1,2-c]pyrimidines with dual SSRI and 5-HT1A activity. part 3 was written by Herold, Franciszek;Chodkowski, Andrzej;Izbicki, Lukasz;Turlo, Jadwiga;Dawidowski, Maciej;Kleps, Jerzy;Nowak, Gabriel;Stachowicz, Katarzyna;Dybala, Malgorzata;Siwek, Agata;Mazurek, Aleksander P.;Mazurek, Andrzej;Plucinski, Franciszek. And the article was included in European Journal of Medicinal Chemistry in 2010.Application In Synthesis of 3-(Piperidin-4-yl)-1H-indole This article mentions the following:

A number of 4-aryl-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidines with 3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole or 2-methyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole residues were synthesized for further investigation of SAR in a group of pyrido[1,2-c]pyrimidine derivatives with dual 5-HT1A/SERT activity. Synthesized compounds were found to be potent ligands for both 5-HT1A and SERT with Ki ranging from 28.3 to 642 nM and 42.4 nM to 1.8 μM, resp. Moreover some compounds were found to be selective agonists, while compound I as an antagonist of 5-HT1A presynaptic receptors in the inducible hypothermia test in mice. In the experiment, the researchers used many compounds, for example, 3-(Piperidin-4-yl)-1H-indole (cas: 17403-09-7Application In Synthesis of 3-(Piperidin-4-yl)-1H-indole).

3-(Piperidin-4-yl)-1H-indole (cas: 17403-09-7) belongs to piperidine derivatives. The piperidine ring can be found not only in more than half of the currently known structures of alkaloids, but also in many natural or synthetic compounds with interesting biological activities. The piperidine and polyhydroxylated indolizidine derivatives have shown to be promising α-glucosidase inhibitors. The former are analogs of DNJ with an improved α-glucosidase inhibitory profile than that of DNJ. Boisson et al.Application In Synthesis of 3-(Piperidin-4-yl)-1H-indole

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem