Synthetic Route of 2213-43-6, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.2213-43-6, Name is 1-Aminopiperidine, molecular formula is C5H12N2. In a article£¬once mentioned of 2213-43-6
Synthesis and antiproliferative activity of novel (+)- usnic acid analogues
Twenty one novel (+)- usnic acid-based analogues belonging to three classes such as enamines, imines, and pyrazoles were synthesized. All the synthesized compounds were characterized by their spectral data (1H NMR, 13C NMR, IR, and HRMS). The synthesized compounds were evaluated for their antiproliferative activity against a panel of four human cancer cell lines including HeLa (cervix), MDA-MB-231 (breast), A549 (lung), and MiaPaca (pancreas) by employing SRB cell proliferation assay. Screening results indicated that all synthesized compounds showed enhanced activity than the parent compound. Most significantly, compounds 2e and 4a showed potent antiproliferative activity against all the cancer cell lines tested. Compounds 2e and 4a arrested the cell cycle in G2/M phase and induced apoptosis in HeLa cells. In view of significant antiproliferative activity, compounds 2e and 4a can be considered as lead molecules for further development. (Figure presented.).
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 2213-43-6, and how the biochemistry of the body works.Synthetic Route of 2213-43-6
Reference£º
Piperidine – Wikipedia,
Piperidine | C5H602N – PubChem