Benzotriazole-Mediated Stereoselective Olefination of Carboxylic Esters: Transformation of α-Amino Acid Esters into Chiral Allylamines was written by Katritzky, Alan R.;Cheng, Dai;Li, Jianqing. And the article was included in Journal of Organic Chemistry in 1998.Category: piperidines This article mentions the following:
Diastereoselective trans-olefinations of carboxylic esters have been accomplished using benzylic or allylic benzotriazole derivatives to prepare α-(benzotriazol-1-yl) ketones, subsequent reduction of the ketones, and finally low-valent titanium-effected dehydroxybenzotriazolylation. In a similar manner, N-protected α-amino acid esters give allylamines with virtually full retention of chirality. Mechanistic aspects of the dehydroxybenzotriazolylation are discussed. In the experiment, the researchers used many compounds, for example, Ethyl 1-methylpipecolinate (cas: 30727-18-5Category: piperidines).
Ethyl 1-methylpipecolinate (cas: 30727-18-5) belongs to piperidine derivatives. Piperidine is a saturated organic heteromonocyclic parent, an azacycloalkane, a secondary amine and a member of piperidines. Piperidine derivatives are being utilized in different ways as anticancer, antiviral, antimalarial, antimicrobial, antifungal, antihypertension, analgesic, anti-inflammatory, anti-Alzheimer, antipsychotic and/or anticoagulant agents.Category: piperidines
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem