Dobi, Zoltan et al. published their research in ChemSusChem in 2019 | CAS: 95798-22-4

Benzyl 3-hydroxypiperidine-1-carboxylate (cas: 95798-22-4) belongs to piperidine derivatives. Piperidine is a saturated organic heteromonocyclic parent, an azacycloalkane, a secondary amine and a member of piperidines. Piperidine derivatives bearing a masked aldehyde function in the 钄?position are easily transformed into quinolizidine compounds through intramolecular reductive amination.Category: piperidines

Carbamate Synthesis Using a Shelf-Stable and Renewable C1 Reactant was written by Dobi, Zoltan;Reddy, B. Narendraprasad;Renders, Evelien;Van Raemdonck, Laurent;Mensch, Carl;De Smet, Gilles;Chen, Chen;Bheeter, Charles;Sergeyev, Sergey;Herrebout, Wouter A.;Maes, Bert U. W.. And the article was included in ChemSusChem in 2019.Category: piperidines This article mentions the following:

4-Propylcatechol carbonate is a shelf-stable, renewable C1 reactant, which is easily prepared from renewable 4-propylcatechol (derived from wood) and di-Me carbonate (derived from CO2) using a reactive distillation system. In this work, the 4-propylcatechol carbonate was used for the two-step synthesis of carbamates I [R1 = Et, cyclopropyl, PhCH2, etc., R2 = H; R1R2 = (CH2)3, (CH2)4, (CH2)2O(CH2)2, etc.; R3 = Me, Et, PhCH2, L-menthyl, etc.] under mild reaction conditions. In the first step, 4-propylcatechol carbonate reacted with an alc. R3OH at 50-80 鎺矯 in the presence of a Lewis acid catalyst, such as Zn(OAc)2璺? H2O, to afford the corresponding carbonates II. No solvent was used in the reactions with liquid alcs., whereas 2-methyltetrahydrofuran was used as solvent in reactions with solid alcs. In the second step, the carbonate intermediates II reacted with various amines R1R2NH at room temperature in 2-methyltetrahydrofuran, forming the target carbamates I and the byproduct 4-propylcatechol, which could be recycled into a carbonate reactant. In the experiment, the researchers used many compounds, for example, Benzyl 3-hydroxypiperidine-1-carboxylate (cas: 95798-22-4Category: piperidines).

Benzyl 3-hydroxypiperidine-1-carboxylate (cas: 95798-22-4) belongs to piperidine derivatives. Piperidine is a saturated organic heteromonocyclic parent, an azacycloalkane, a secondary amine and a member of piperidines. Piperidine derivatives bearing a masked aldehyde function in the 钄?position are easily transformed into quinolizidine compounds through intramolecular reductive amination.Category: piperidines

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem