N-Acetyl-N-acyl-3-aminoquinazolinones as chemoselective acetylating agents was written by Atkinson, Robert S.;Barker, Emma;Sutcliffe, Michael J.. And the article was included in Chemical Communications (Cambridge) in 1996.Reference of 4045-22-1 This article mentions the following:
The title compounds, e.g. I, are highly selective acetylating agents for primary amines in the presence of secondary amines and, in particular, for the less sterically hindered of two different secondary amines. In the experiment, the researchers used many compounds, for example, 1-(4-Hydroxypiperidin-1-yl)ethanone (cas: 4045-22-1Reference of 4045-22-1).
1-(4-Hydroxypiperidin-1-yl)ethanone (cas: 4045-22-1) belongs to piperidine derivatives.Piperidine is a key saturated heterocyclic scaffold found in several of the top-selling small molecule pharmaceuticals and natural alkaloids, with a diverse range of biological activities. Some chemotherapeutic agents have piperidine moiety within their structure, foremost among them, vinblastine and raloxifene.Reference of 4045-22-1
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem