Copper-Catalyzed Arylative Meyer-Schuster Rearrangement of Propargylic Alcohols to Complex Enones using Diaryliodonium Salts was written by Collins, Beatrice S. L.;Suero, Marcos G.;Gaunt, Matthew J.. And the article was included in Angewandte Chemie, International Edition in 2013.Product Details of 33439-27-9 This article mentions the following:
A new approach to transform readily accessible propargylic alcs. into α-aryl-α,β-unsaturated carbonyls, e.g., I, using diaryliodonium salts and copper catalysis has been developed. This protocol operates under mild conditions and provides a broad scope of the desired enone products in good yields and high selectivity for the E-isomer. The highly functionalized E-trisubstituted enone products are versatile synthetic intermediates and can be readily transformed into important heterocyclic motifs. In the experiment, the researchers used many compounds, for example, 1-Tosylpiperidin-4-one (cas: 33439-27-9Product Details of 33439-27-9).
1-Tosylpiperidin-4-one (cas: 33439-27-9) belongs to piperidine derivatives. Piperidine has a role as a reagent, a protic solvent, a base, a catalyst, a plant metabolite, a human metabolite and a non-polar solvent. The piperidine and polyhydroxylated indolizidine derivatives have shown to be promising α-glucosidase inhibitors. The former are analogs of DNJ with an improved α-glucosidase inhibitory profile than that of DNJ. Boisson et al.Product Details of 33439-27-9
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem