Total synthesis of balanol: a potent protein kinase C inhibitor of fungal origin was written by Adams, C. P.;Fairway, S. M.;Hardy, C. J.;Hibbs, D. E.;Hursthouse, M. B.;Morley, A. D.;Sharp, B. W.;Vicker, N.;Warner, I.. And the article was included in Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry in 1995.Product Details of 33439-27-9 This article mentions the following:
The total synthesis of the fungal metabolite balanol, a potent inhibitor of protein kinase C, is described. The synthesis includes a novel synthesis of 3-amino-4-hydroxyazepanes via a directed ring expansion of 3-bromopiperidin-4-ones. In the experiment, the researchers used many compounds, for example, 1-Tosylpiperidin-4-one (cas: 33439-27-9Product Details of 33439-27-9).
1-Tosylpiperidin-4-one (cas: 33439-27-9) belongs to piperidine derivatives. The piperidine moiety constitutes an important building block for the synthesis of a variety of bioactive natural products, alkaloids and other drugs. Some chemotherapeutic agents have piperidine moiety within their structure, foremost among them, vinblastine and raloxifene.Product Details of 33439-27-9
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem