Morpholinosulfur Trifluoride (Morph-DAST)-Mediated Rearrangement in the Fluorination of Cyclic α,α-Dialkoxy Ketones toward 1,2-Dialkoxy-1,2-difluorinated Compounds was written by Surmont, Riccardo;Verniest, Guido;De Groot, Alex;Thuring, Jan Willem;De Kimpe, Norbert. And the article was included in Advanced Synthesis & Catalysis in 2010.Related Products of 33439-27-9 This article mentions the following:
The deoxofluorination of cyclic α,α-dialkoxy ketones with morpholinosulfur trifluoride gave title compounds, e.g. I (Z = BocN, CH2, O, etc.). The reaction proceeds via a 1,2-alkoxy migration leading to mixtures of cis- and trans-isomers. In the experiment, the researchers used many compounds, for example, 1-Tosylpiperidin-4-one (cas: 33439-27-9Related Products of 33439-27-9).
1-Tosylpiperidin-4-one (cas: 33439-27-9) belongs to piperidine derivatives. The piperidine moiety constitutes an important building block for the synthesis of a variety of bioactive natural products, alkaloids and other drugs. The piperidine and polyhydroxylated indolizidine derivatives have shown to be promising α-glucosidase inhibitors. The former are analogs of DNJ with an improved α-glucosidase inhibitory profile than that of DNJ. Boisson et al.Related Products of 33439-27-9
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem