Analogues of arginine vasopressin modified in the N-terminal part of the molecule with pipecolic acid isomers was written by Sobolewski, Dariusz;Prahl, Adam;Slaninova, Jirina;Lammek, Bernard. And the article was included in Advances in Experimental Medicine and Biology in 2009.Synthetic Route of C21H21NO4 The following contents are mentioned in the article:
This study evaluated ten newly designed analogs of arginine vasopressin modified in the N-terminal part of the mol. with pipecolic acid (Pip) isomers. In general, the data was not impressive in terms of biol. activities of the reported analogs, but it provides important information on structure-activity relationships and response of the L- or D-Pip-containing peptides to standard trifluoroacetic acid cleavage conditions. This study involved multiple reactions and reactants, such as (S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidine-2-carboxylic acid (cas: 86069-86-5Synthetic Route of C21H21NO4).
(S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidine-2-carboxylic acid (cas: 86069-86-5) belongs to piperidine derivatives. Piperidine is a metabolite of cadaverine, a polyamine found in the human intestine. Some chemotherapeutic agents have piperidine moiety within their structure, foremost among them, vinblastine and raloxifene.Synthetic Route of C21H21NO4
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem