Carpino, Louis A.’s team published research in Journal of Organic Chemistry in 37 | CAS: 35661-58-6

Journal of Organic Chemistry published new progress about 35661-58-6. 35661-58-6 belongs to piperidines, auxiliary class Piperidine,Benzene, name is 1-((9H-Fluoren-9-yl)methyl)piperidine, and the molecular formula is C19H21N, COA of Formula: C19H21N.

Carpino, Louis A. published the artcile9-Fluorenylmethoxycarbonyl amino-protecting group, COA of Formula: C19H21N, the publication is Journal of Organic Chemistry (1972), 37(22), 3404-9, database is CAplus.

The 9-fluorenylmethoxycarbonyl group (FMOC) is a new amino-protecting group, which is stable toward acids and catalytic hydrogenation but readily cleaved under mildly basic, non-hydrolytic conditions. The FMOC group may be introduced by reaction of the amine with 9-fluorenylmethyl chloroformate. A number of protected amino acid derivatives were coupled with other amino acids or esters by use of the corresponding N-hydroxypiperidine esters. Deblocking of the FMOC group was carried out with liquid NH3 or at room temperature with piperidine, morpholine, ethanolamine. etc.

Journal of Organic Chemistry published new progress about 35661-58-6. 35661-58-6 belongs to piperidines, auxiliary class Piperidine,Benzene, name is 1-((9H-Fluoren-9-yl)methyl)piperidine, and the molecular formula is C19H21N, COA of Formula: C19H21N.

Referemce:
https://en.wikipedia.org/wiki/Piperidine,
Piperidine | C5H11N – PubChem