Crich, David published the artcileDirect Chemical Synthesis of the β-
The direct syntheses of a β-(1→2)-mannooctaose and of a β-(1→4)-mannohexaose are reported by means of 4,6-O-benzylidene-protected β-mannosyl donors. The synthesis of the (1→2)-mannan was achieved by means of the sulfoxide coupling protocol, whereas the (1→4)-mannan was prepared using the analogous thioglycoside/sulfinamide methodol. In the synthesis of the (1→4)-mannan, the glycosylation yields and stereoselectivities remain approx. constant with increasing chain length, whereas those for the (1→2)-mannan consist of two groups with the formation of the tetra- and higher saccharides giving yields and selectivities consistently lower than those of the lower homologs. The decrease in yield after the trisaccharide in the (1→2)-mannan synthesis is attributed to steric interference by the n-3 residue and is consistent with the collapsed, disordered structure predicted by early computational work. The consistently high yields and selectivities seen in the synthesis of the (1→4)-mannan are congruent with the more open, ordered structure originally predicted for this polymer. The lack of order in the structure of the (1→2)-mannan, as compared to the high degree of order in the (1→4)-mannan, is also evident from a comparison of the NMR spectra of the two polymers and even from their phys. nature: the (1→2)-mannan is a gum and the (1→4)-mannan is a high melting solid.
Journal of the American Chemical Society published new progress about 4972-31-0. 4972-31-0 belongs to piperidines, auxiliary class Piperidine,Benzene, name is 1-(Phenylsulfinyl)piperidine, and the molecular formula is C11H15NOS, Safety of 1-(Phenylsulfinyl)piperidine.
Referemce:
https://en.wikipedia.org/wiki/Piperidine,
Piperidine | C5H11N – PubChem