Valenta, Vladimir published the artcilePotential neuroleptics of the orthopramide series; synthesis of heterocyclic 5-amino-2-methoxybenzamides and of some related compounds, Name: 1-Benzylpiperidin-4-amine dihydrochloride, the main research area is neuroleptic aminomethoxybenzamide heterocyclic preparation.
Condensation of 2,5-MeO(O2N)C6H3COCl with heterocyclic amines and hydrazines gave the title derivatives I (R = NO2, n = 0, 1) and II (R = NO2; Z = NH, X = CH, N; Z = bond, X = N). Reduction of I and II (R = NO2) with Raney Ni gave amino derivatives I and II (R = NH2). I (R = NHMe, n = 1) and II (R = NHMe, Z = NH, X = CH) were prepared via tosyl derivatives All prepared compounds I and II were tested as potential neuroleptics. Only compounds II (Z = NH, X = CH) show mild activity.
Collection of Czechoslovak Chemical Communications published new progress about Tranquilizers. 1205-72-7 belongs to class piperidines, name is 1-Benzylpiperidin-4-amine dihydrochloride, and the molecular formula is C12H20Cl2N2, Name: 1-Benzylpiperidin-4-amine dihydrochloride.
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem